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Robert Caro on Power: Robert Moses, Lyndon Johnson and the Will to Build
Robert Caro, who has spent 50 years writing about Robert Moses and Lyndon Johnson, tells Dwarkesh Patel what he learned about power, ruthlessness and getting big things built.…
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AI Agent Performs Brain Surgery on a Mouse: What It Chose and Refused
An AI agent chose a gene therapy, picked a brain target and injected it into a living mouse with epilepsy, then refused to let its operator override a…
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Eric Glyman: Why Ramp Is Worth $60 Billion and Software Became Money
Ramp co-founder and co-CEO Eric Glyman explains why investors valued the company at $60 billion, why AI tokens turned software into a financial product, and why Ramp is…
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Neal Stephenson on AI, the Atomic Race, and Why the Primer Is Hard
Neal Stephenson tells Ashlee Vance why the AI boom blindsided him, why he still thinks it is an S-curve, and why building the primer from The Diamond Age…
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Guillermo Rauch: Raising Kids Who Think, and Why Trust Is the AI Moat
Vercel CEO Guillermo Rauch tells Delphi why trust is the moat after AGI, why agents are now his customers, and how he is raising six kids to think…
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Jev for Images: TypeSafe’s Decision Model Learns to See, Fast and Cheap
Jev for Images lets TypeSafe AI’s tiny decision model look at photos, screenshots and scanned pages, answering yes or no, picking a label, scoring, or drawing a box…
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Spawn: How 10 People Ship 77,000 Changes a Month With an AI Agent Fleet
Spawn, a ten-person game engine startup, ships about 77,000 code changes a month by running a permanent fleet of AI agents on $3.1 million of Claude tokens. In…
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Sam Altman: Why a Trillion AIs Beat One Single Superintelligence
Sam Altman told Stripe co-founder John Collison why he would rather see a trillion slightly superhuman AIs join society than one AI with a trillion IQ. Over a…
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Gemini 4 Carbon: Google’s New Frontier Model for Cyber Defense and Coding
Google DeepMind’s Gemini 4 Carbon is a new frontier model built for cyber defense and long-horizon coding, released first to vetted security teams rather than the public. Announced…
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Tobi Lütke: Why Shopify Welcomes the AI Agents Amazon Blocks
Shopify CEO Tobi Lütke explains why Shopify embraced Meta’s Muse shopping agent while Amazon blocked it, and how AI agents will change who gets paid in commerce. In…
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David Deutsch: Why Pessimism Sounds Smart and AI Doom Gets It Wrong
Physicist David Deutsch tells Chris Williamson why pessimism passes for sophistication, why AI doom repeats the nuclear power mistake, and why LLMs will not become AGI. In this…
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Bill Ackman: Why Permanent Capital Is an Investor’s Biggest Edge
Bill Ackman tells Nicolai Tangen why permanent capital is Pershing Square’s biggest edge and how Howard Hughes becomes a Berkshire-style insurer. In this episode of In Good Company,…