October 12, 2026
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Perplexity CEO Aravind Srinivas: Why Tiny Companies Could Drive US Growth
Perplexity CEO Aravind Srinivas argues that small, AI-native companies will drive American growth, and that AI agents belong on hardware you already own. He makes the case to…
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Muse Wonder: Zuckerberg and Alexandr Wang on Meta’s $100B AI Bet
Mark Zuckerberg and Alexandr Wang tell John Collison how Meta built Muse Wonder and why it committed over $100 billion before the model existed. The conversation is the…
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Cal Newport on AI Brain Rot: The Math Paper and 3 Rules for Using LLMs
Cal Newport explains a new paper that models LLM use as a spreading virus, and draws from it three ways to keep people from depending on AI to…
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Recursive Self-Improvement: MakerMaker’s Founders on What Counts as RSI
MakerMaker.AI co-founders Dhaval Adjodah and Owen He tell a16z’s Martin Casado that recursive self-improvement is already showing up in their results: an AI system that gets better while…
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Martin Shkreli on All-In: The Quantum Short and Why AI Won’t Find Drugs
Martin Shkreli told the All-In Podcast he has lost millions shorting quantum computing, expects no AI drug within ten years, and picks Meta as the AI winner. In…